Hide and seek: the secret identity of the phosphatidylserine receptor

نویسندگان

  • Patrick Williamson
  • Robert A Schlegel
چکیده

Phosphatidylserine on the dying cell surface helps identify apoptotic cells to phagocytes, which then engulf them. A candidate phagocyte receptor for phosphatidylserine was identified using phage display, but the phenotypes of knockout mice lacking this presumptive receptor, as well as the location of the protein within cells, cast doubt on the assignment of this protein as the phosphatidylserine receptor.

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عنوان ژورنال:
  • Journal of Biology

دوره 3  شماره 

صفحات  -

تاریخ انتشار 2004